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From System Biology to Translational Medicine
                                       ---6th Sino-Finn Life Science Forum

17-18, August, 2015
Lecture Hall 2, Biomedicum Helsinki,  Haartmaninkatu 8, Helsinki, Finland




Program


08:00 – 09:00                      Registration (Entrance Hall, Biomedicum Helsinki)


09:00 – 09:45                      Opening & Welcome
 

09:00 – 09:05                      Opening remarks

                                           Gonghong Wei, University of Oulu, FI
                                           Overview of the meeting participants, speakers, organizers and sponsors
 

09:05 – 09:15                      Welcome words
                                           Tomi Mäkelä, University of Helsinki, FI
                                           Vision of life science research in Helsinki, collaboration with China
 

09:15 – 09:25                      Welcome words
                                           Olli A. Jänne, Biocenter Finland, FI
                                           Introduction of Biocenter Finland and collaboration with China
 

09:25 – 09:35                      Opening remarks
                                           Deyin Guo, Wuhan University, CN
                                           Introduction of life sciences in China and collaboration with Finland


09:35 – 09:45      Greetings from the Embassy of China in Finland


Session 1:                   Human health and organ morphogenesis

09:45 – 10:10                      Sulin Cheng
                                           Shanghai Jiao Tong University, CN
                                           New paradigms and challenges in health - Can bio-informatics be the solution?


10:10 – 10:35                      Eero Castren

                                           Neuroscience Center, University of Helsinki, FI
                                           Induction of neuronal plasticity in adult brain


10:35 – 11:00                      Coffee & Tea break 


 

11:00 – 11:25                      Juhani Knuuti
                                           University of Turku and Turku University Hospital, FI
                                           
                                           PET imaging from mice to men

 

11:25 – 11:40                      Li Ma
                                           Neuroscience Center, University of Helsinki, FI
                                           Brain immune network in autism and schizophrenia-related animal model

                                                                                      

11:40 – 11:55                      Ziqi Zhu
                                           Zhongguancun Office-Finland, CN

 

11:55 – 12:00                      Transition to Lecture Hall 1

 

Biomedicum Helsinki Seminar

 12:00 – 13:00                      Ralf Adams
                                           Max Planck Institute for Molecular Biomedicine, Munich, GE
                                         Organ-specific specialization of blood vessel growth and function
 

13:00 – 14:00                      Lunch break


Session 2:                   Computational systems biology for clinical research
 
14:00 – 14:25                      Sampsa Hautaniemi
                                           Genome-scale Biology Program, University of Helsinki, FI
                                           Analysis and integration of large-scale medical data

14:25 – 14:50                      Bairong Shen
                                          Center for Systems Biology, Soochow University, CN
                                           Network based analysis of the gene society

14:50 – 15:15                      Teemu Kivioja

                                           Genome-scale Biology Program, University of Helsinki, FI
                                           Understanding transcription factor binding by combining in vitro models and evolutionary conservation
 

15:15 – 15:30                      Jing Tang
                                           Institute for Molecular Medicine Finland, FI
                                           Network-based drug discovery for personalized medicine – data integration, model prediction and mechanistic understanding


15:30 – 15:45                      Chengyu Liu
                                           Genome-scale Biology Program, University of Helsinki, FI
                                           Identification of survival associated network modules
 

15:45 – 17:45                     Poster Session (with refreshments)

 

Tuesday, August 18, 2015


Session 3:                   Individualized and translational cancer research


09:00 – 09:25                      Olli Kallioniemi
                                           Institute for Molecular Medicine Finland, FI
                                           Individualized systems medicine in guiding treatment of cancer patients

09:25 – 09:50                      Lijun Di

                                           Faculty of Health Sciences, University of Macau, CN
                                           Functional studies of CtBP in Cancer

09:50 – 10:15                      Marko Hyytiäinen,
                                           Translational Cancer Biology, University of Helsinki, FI
                                           The role of netrins in glioblastoma

10:15 – 10:40                      Yulun Huang

                                           Soochow University, CN
                                           Autoantibodies against MGMT as a serological biomarker in the diagnosis and prognosis of glioma


10:40 – 11:00                     Coffee & Tea break 


11:00 – 11:25                      Krister Wennerberg
                                           Institute for Molecular Medicine Finland, FI
                                           Axitinib effectively targets gatekeeper mutant chronic myeloid leukemia


11:25 – 11:50                      Tapio Visakorpi
                                           Prostate Cancer Research Center, University of Tampere, FI
                                           Molecular mechanisms driving castration resistance and metastasis in prostate cancer
 

11:50 – 12:15                      Gonghong Wei
                                           Biocenter Oulu/FBMM, University of Oulu, FI
                                           Translating prostate cancer GWAS discoveries to the clinic
 

12:15 – 12:30                      Shuliang Chen
                                           School of Basic Medical Sciences, Wuhan University, CN
                                           The tumor suppressor VHL is involved in innate antiviral responses
 

12:30 – 13:30                      Lunch break

Session 4:                   Disease modeling and translational research

13:30 – 13:55                      Deyin Guo

                                           School of Basic Medical Sciences, Wuhan University, CN
                                           SARS and MERS coronaviruses: Novel molecular mechanisms and potential drug targets

13:55 – 14:20                      Pekka Katajisto

                                           Institute of Biotechnology, University of Helsinki, FI
                                           Asymmetric organelle apportioning by dividing stem cells

14:20 – 14:45                      Zhi Jane Chen

                                           Turku Centre for Biotechnology, University of Turku, FI
                                           Transcriptional regulation and signaling network of the development of helper T cell subsets


14:45 – 15:10                      Li Tian
                                           Neuroscience Center, University of Helsinki, FI
                                           Mind-immune connection: understanding it from the systems biological perspective


15:10 – 15:30                     Coffee & Tea break


15:30 – 15:55                      Seppo Vainio
                                           Biocenter Oulu/InfoTech Oulu, University of Oulu, FI
                                           Towards Nanocommunication Emergence of Systems Biology - a Kidney Organogenesis Centric View Point


15:55 – 16:20                      Qiushui He
                                           University of Turku, FI; Capital Medical University, CN
                                           Genetics of Toll-like Receptors and Disease Susceptibility

16:20 – 16:35                      Mahmoud Elkhwanky
                                           Faculty of Medicine, University of Oulu, FI
                                           Coactivator PGC-1α regulates vitamin D metabolizing enzymes CYP2R1 and CYP24A1 through ERRα


16:35 – 16:50                      Yan Yan
                                           Genome-scale Biology Program, University of Helsinki, FI
                                           SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signaling


16:50 – 17:00                      Discussion
 

17:00 – 17:10                      Closing remarks
                                           Bairong Shen, Soochow University, CN

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