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Position This Week 20110307-20110313

3/13/2011

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Position This Week 20110307-20110313

INFO1
A MSc-level project researcher position is available in the field of cell biology/developmental biology at the Institute of Biotechnology, University of Helsinki. The project investigates cellular mechanisms regulating epithelial morphogenesis in development and disease using advanced confocal microscopy and live tissue imaging methods. Application deadline is March 11, 2011.

INFO2

PhD student position is available in virology/cell biology at the Cell and Molecular Biology Program, Institute of Biotechnology, University of Helsinki. The project investigates the formation, function and structure of RNA virus replication complex using advanced molecular and cell biology techniques. Application deadline is March 15.
Tutkijalääkärille olisi heti tarjolla mielenkiintoista tutkimustyötä kliinisten lääketutkimusten parissa. Työ sisältää sekä lääkeyritysten tuotekehitykseen liittyvää tilaustutkimusta että akateemista tieteellistä tutkimusta. Työssä on mahdollisuus kokonaiseen väitöskirjaprojektiin allekirjoittaneen ohjauksessa. Jo väitelleelle kollegalle tarjotaan mahdollisuus tieteelliseen lisäpätevöitymiseen. Työhön liittyy mahdollisuus kliinisen farmakologian ja lääkehoidon erikoislääkärikoulutukseen. Yhteydenotot ja lisätiedot sähköpostitse: mika.scheinin-at-utu.fi. Lisätietoja varten kts. myös www.crst.fi. (18.2.2011)

INFO3


Graduate student position in osteoimmunology research group at the Department of Medical Biochemistry and Genetics, University of Turku. Our group is focused on the molecular mechanisms regulating osteoblast differentiation as well as the interplay between bone cells and the immune system. Applications must be received by March 31, 2011.

INFO4


PhD student position at the Department of Biomedical Technology, University of Oulu. Applications are invited for interested and motivated students from various fields. For example, the suitable background could be biomedical engineering, medical technology, medical physics, medicine, or other relevant field. Candidates with a recently completed M.Sc. degree, or who are currently finishing their M.Sc. degree, are invited to apply. Deadline for application is April 8th, 2011.


INFO5

Music is a fascinating phenomenon. Musical aptitude varies between individuals and it may arise in several different ways. Two research positions are open at the Department of Medical Genetics, University of Helsinki where candidate genes for musical aptitude will be identified using genome-wide scan, gene expression microarray and microRNA analyses and the evolution of the identified variants analysed.

INFO6

There is a vacancy for a software developer at the University of Oulu.

Details are below, and also at:
http://www.oulu.fi/dokumentit/jobs/xtalPiMS_Software_Developer.rtf

OPEN POSITION
Biocenter Oulu, University of Oulu, Finland

Biocenter Oulu (http://www.biocenter.oulu.fi)  is a research institute
focused on biomedical, biochemical and structural biological research. A
vacancy exists at the X-ray core facility of the Biocenter Oulu, University
of Oulu, Finland, in the research group of Professor Rik Wierenga,
Department of Biochemistry, Linnanmaa, Oulu
(http://www.biochem.oulu.fi/tutkimus/wierenga/index.html) to extend
scientific software that is being developed in the UK. The person
appointed will spend some of the working time in the Daresbury Laboratory,
Cheshire, UK, especially in the beginning of the work.

xtalPiMS Software Developer (fixed-term employment)

The xtalPiMS software application provides a database and a web interface to
help protein crystallographers keep track of their work. It connects
upstream to PiMS (Protein Information Management System) and downstream to
structure determination protocols. This vacancy will extend and support this
application for use at the University of Oulu and elsewhere. Part of the
work is to send and receive data related to X-ray diffraction data
collection at synchrotrons, using ISPyB-protocols. Eventually the key data
of the structure solution protocol will also be archived in the database.

Technologies used
The software system includes a relational database, Oracle for some users
and Postgres for others.  The user interface is a Java web application, with
some Ajax. JUnit is used to make test cases.  The project uses Subversion
for source code control, E-mail archives, and an issue tracker. There are
more details at https://cselnx4.dl.ac.uk/docs/howToPiMS.html

Job requirements
You will have an MSc for example in natural science or computing sciences
and at least three years experience of software development, including
experience of enhancing existing software. Experience of the following is
desirable: developing Java web applications, system administration,
collaborating at a distance, test driven development, software testing,
developing software to support life scientists, crystallography. Duties will
include being a user support contact identifying and fixing bugs,
identifying enhancements in communication with scientists at Oulu and
elsewhere, and implementing enhancements, incorporating code into the
distributed software suite, assisting with the public release of software,
development of the code base. Travelling to Daresbury (UK), Diamond, Oxford
(UK) and MAXLAB, Lund (Sweden) will be required for the optimal development
and  implementation of the software.

Conditions
The project will start as soon as the position can be filled; it will be for
two years and might be extended till end of 2013. The starting salary will
be based on the level 8 of the demand level chart for university level
general staff of the salary system of the Finnish Universities. The
job-specific component of the salary being 2333.53 Euro per month and the
salary component based on personal work performance will be added  (maximum
46.3% of the job-specific component). Totally, the monthly starting salary
will be between 2333,53 -2991,59 Euros.

Further information

Further information can be obtained from: Professor Rik Wierenga,
rik.wierenga@oulu.fi, +358 8 5531199 and Chris Morris,
chris.morris@stfc.ac.uk, +44 1925 603689; and also from:
http://www.pims-lims.org, http://www.cse.scitech.ac.uk/ccisb/,
http://www.ccp4.ac.uk.

All applications with a CV and covering letter should be mailed to
University of Oulu, Kirjaamo/Office of Registrar, PO Box 8000 (Street
address: Pentti Kaiteran katu 1), FI-90014 University of Oulu, Finland, by
April 21, 2011, before 3:00 pm. Please write on the envelope "xtalPiMS
software developer". Please indicate how you meet the job requirements
described above as well as your interests for this project and provide the
names and addresses of two references.

INFO7
Ph.D. Student position

Background:
Osteoarthritis (OA) and osteoporosis (OP) are common musculoskeletal diseases. An inverse
relationship between OA and OP has been observed in several studies, i.e., it has been
suggested that OP may protect against OA. Etiological factors for this finding are not
yet understood.

It is also known that bone structure and geometry has a significant impact for the bone
strength, and for the development of OP and the risk of fracture. Consequently, bone
structure and geometry can even predict the development of OP and fracture in the future.
On the other hand, structural properties of subchondral bone and joint geometry are known
to be related to development of OA. However, their clinical significance remains still
unknown. It would be a significant advantage if development of OA could be predicted from
subchondral bone properties and joint geometry.

Aims:
1) To clarify whether an inverse relationship between hip OP and OA is observed in
population-based cohort of ca. 650 patients,
2) To investigate the effect of bone structure and geometry on the hypothesized inverse
relationship between these two diseases, and
3) To investigate the clinical significance of subchondral bone and joint geometry for
prediction of development of OA.

Research environment:
The research will be conducted at the Department of Medical Technology, Institute of
Biomedicine, University of Oulu, Finland (http://www.medicine.oulu.fi/ltek/).

Requirements:
Applications are invited for interested and motivated students from various fields. For
example, the suitable background could be biomedical engineering, medical technology,
medical physics, medicine, or other relevant field. Candidates with a recently completed
M.Sc. degree, or who are currently finishing their M.Sc. degree, are invited to apply.
The experience in medical imaging (e.g. X-ray and ultrasound), biomedical imaging,
digital image analysis and/or finite element modeling (FEM) is an advantage.

Salary:
The salary is defined according to the YPJ salary system of Finnish universities.

Starting date:
June 1st, 2011, or as soon as possible thereafter.

Application:
Please send your application by email to Simo Saarakkala (simo.saarakkala@oulu.fi) by
April 8th, 2011. The application documents should include: 1) A cover letter, 2) Grades
of completed courses and degree certificates, 3) Curriculum Vitae, and 4) Full name and
email address of one referee (preferably a supervisor of M.Sc. thesis).

Contact details:
Please, direct any questions or correspondence to:

Simo Saarakkala, Ph.D.
Research fellow, Adjunct professor
Department of Biomedical Technology
Institute of Biomedicine
University of Oulu, Finland
Email:simo.saarakkala@oulu.fi
Phone: +358-505746681

INFO8

Research Associate / Post-doctoral Fellow

Background:
Osteoarthritis (OA) is a common musculoskeletal disease occurring in all populations. OA
is associated with progressive degeneration of articular cartilage along with abnormal
growth of underlying subchondral bone and cartilage-bone junction. OA may be regarded as
a whole-organ joint disease. However, the complex interplay between inflammatory cells,
synovial lining, articular cartilage and subchondral bone, causing the OA related
tissue-level and cellular-level changes and subsequent clinical symptoms, is still poorly
understood. Therefore, novel information is needed to better understand the etiology of
OA, especially the earliest phases of the disease.

Aim:
To experimentally clarify the early phases of OA in tissue and cellular level by applying
novel multimodal biomedical imaging and tissue analysis techniques.

Research environment:
The research will be conducted at the Institute of Biomedicine, University of Oulu,
Finland (http://www.medicine.oulu.fi/biolaak/).

Length of the position:
One year + possibility to an extension for second year.

Requirements:
The suitable background for a successful candidate would be biophysics, biochemistry,
biology, biotechnology, medical physics, biomedical engineering, or other relevant field.
The experience in biomedical imaging, microscopical techniques and/or biomechanical
tissue characterization is an advantage. Candidates with a recently completed Ph.D.
degree (preferably<  3 years), or who are finishing their Ph.D. degree, are invited to
apply.

Salary:
The salary is defined according to the YPJ salary system of Finnish universities.

Starting date:
July 1st, 2011, or as soon as possible thereafter.

Application:
Please, send your application by email to principal investigator Simo Saarakkala
(simo.saarakkala@oulu.fi) by April 15th, 2011. The application documents should include:
1) A brief introductory letter describing an earlier research experience, 2) Curriculum
vitae and degree certificates, 3) List of scientific publications, and 4) Full names and
e-mail addresses of two referees.

Contact details:
Please, direct any questions or correspondence to:

Simo Saarakkala, Ph.D.
Principal investigator, Adjunct professor
Department of Biomedical Technology
Institute of Biomedicine
University of Oulu, Finland
Email:simo.saarakkala@oulu.fi
Phone: +358-505746681

INFO9
Unit of Metabolism at Minerva Research Institute, Biomedicum Helsinki, is looking for a post-doctoral research fellow. We are studying the interaction between fatty acid and glucose metabolism, and the mechanisms of fatty acid induced insulin resistance in skeletal muscle. Send in your application as soon as possible, at the latest by March 15th, 2011.

INFO 10

Orion Corporation is a Finnish listed company, which develops, manufactures and markets
pharmaceuticals, active pharmaceutical ingredients and diagnostic tests for global markets. We are looking for a enthusiastic scientist with fresh interests and new ideas. You have a Ph.D. degree and experience from in vitro and in vivo cancer research, possibly in the field of breast and prostate cancer. Our department (Oncology and Critical Care Research in Turku) focuses its activities to the identification and nonclinical characterization of promising drug leads and candidates. Deadline for applications is March 20, 2011.
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