From Biocenter Viikki News


GENERAL INFORMATION The 2nd Sino-Finn Life Science Forum will be held in August 23 - 28, 2009 in Finland. This unique event is organised by Helsinki Graduate School of Biotechnology and Molecular Biology (GSBM) and Biocenter Finland Research Organisation. The event aims to promote bi-national research collaboration and training in biosciences between China and Finland and is a continuum to the First Sino-Finn Life Science Forum held in Wuhan, Suzhou and Shanghai in October 2008. 

Chinese Principal Investigators in the Universities of Wuhan, Suzhou, and Shanghai Institutes of Biological Sciences (Chinese Academy of Sciences) are invited to participate into the 2nd Sino-Finn Life Science Forum in Finland in an effort to enhance successful research collaboration between Finnish and Chinese research groups and to give a firm bases to student exchange programmes between the two countries. This event provides a good opportunity for Chinese Principal Investigators to familiarize themselves with the international level biochemical, biotechnological and biomedical research that is conducted in the Finnish research groups within the Biocenter Finland Research Organisation. The one week’s programme will include a scientific symposium in Helsinki, visits to Finnish research groups, and a visit to Karolinska Institutet in Stockholm, Sweden.

Sino-Finn Symposium 2009 in Helsinki
A whole-day symposium 24.8.2009, starting at 9 am in Viikki, Info Center, Auditorium 2 (Viikinkaari 11). A buffet available at the end of the Symposium at 4 pm. See the program here.

ENTATIVE PROGRAM Sunday, August 23 Arrival in Helsinki, Finland.
- accommodation arrangements Monday, August 24   2nd Sino-Finland Life Science Forum in Helsinki
- keynote speakers from Finland and China
See the program here >>> Tuesday, August 25 Visits to research institutes in Helsinki.
Ferry cruise to Stockholm, arrival on Wednesday morning.    Wednesday,  August 26 Visit to Karolinska Institutet in Stockholm. 
Ferry cruise back to Helsinki, arrival on Thursday morning. Thursday, August 27 Visits to research groups in Finland.
- each PI chooses the groups based on his/her interests Friday, August 28  Research group visits continue.
- returning to Helsinki and to China More detailed programme will be available later. The programme will, to some extent, be tailored according to research areas and interests of the participating PI’s.

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    10月29日，由苏州大学系统生物学中心主办的第一届中国-芬兰生命科学论坛(苏州)在苏州红楼会议中心隆重召开。中国芬兰两国的生命科学家相聚在风景如画的 古城苏州，举办第一届中芬生命科学论坛、畅谈生命科学前沿、探索生命科学难题。苏州大学张学光副校长以及系统生物学研究中心、医学部、生物技术研究所等有关单 位的负责同志出席了会议。



    这次会议是两国科学家的第一次国家层面上的科学家面对面的交流，会议将在武汉、苏州和上海三地进行， 是中芬生命科学家的一次盛会，参加第一届中国-芬兰生命科学论坛（苏州）的芬兰方代表包括研究生院负责人、教授和博士生18名，分别来自芬兰的赫尔辛基、 图尔库、坦佩雷、奥卢等主要城市的生物研究中心。其中包括芬兰著名的系统生物学学家、赫尔辛基生物技术和分子生物学研究生院的Jussi Taipale 教授； 赫尔辛基生物技术和分子生物学研究生院院长、细胞生物学家Pekka Lappalainen 教授；赫尔辛基大学维克（Viikki）生命科学研究生院院长、病毒生物学家Dennis Bamford教授。中方代表有苏州大学数学学院、系统生物学研究中心、医学部、生物技术研究所，以及武汉大学、同济大学的师生共80多名。苏州论坛的论 题为“癌症、免疫和系统生物学” 。

    自从人类基因组计划实施以来，生命科学的发展日新月异，面对复杂的生命现象，国际间的大协作、不同学科背景的共同攻关已成为攻克生命科学难题的必要手段。 苏大为此整合组建了医学部以促进协作研究，成立了系统生物学中心，其宗旨在于促进不同学科的交叉交流，共同攻关。

    中国的生命科学目前正在走向国际化、走向国际研究的前沿，加上生命科学研究本身的复杂性， 使得我们的生命科学研究不可能闭门造车、必须与国际一流的学术团体进行深入交流，包括学术讨论、学术互动，共同申请经费、共同解决难题。 在相互学习和取长补短、相互合作和切磋的基础上， 共同提升和发展。



  


大会报告议程

8:30-9:00

Opening session chaired by SHEN Bairong

Opening ceremony

Chair:  SHEN Bairong

Opening Remark by ZHANG Xueguang

Opening Remark by Pekka Lappalainen

 

9:00-9:30

Photo session

 

 

Section 1: Chair Dennis Bamford

 

9:30-10:15

Jussi Taipale, Helsinki Graduate School in Biotechnology and Molecular Biology

Analysis of Hedgehog signaling pathways by systems biology

 

10:15-10:45

Haiyun Wang, School of Life Science, Tongji University

Clinical information driven ensemble clustering for inferring robust tumor subtypes

 

10:45-11:00  Coffee break

 

Section 2: Chair Pekka Lappalainen

 

11:00-11:30

Kati Waltering , Tampere Graduate School in Biomedicine and Biotechnology

Identification of androgen receptor (AR) target genes putatively involved in the emergence of hormone-refractory prostate cancer.

 

11:30-12:00

Alfonso Urbanucci, Tampere Graduate School in Biomedicine and Biotechnology  ChIP on sequencing using LNCaP cells overexpressing AR   

 

12:00 - 12:30 

Bairong Shen, Center for systems biology Soochow Univeristy

Computational models for disease associated amino acid mutations and mutated biological systems

 

12:30-13:30 Lunch

 

Section 3: Chair Tero Ahola

 

13:30-14:15

Xueguang Zhang: Institute of Biotechonology, Soochow University.

Cancer immunoediting and costimulatory molecules

 

14:15-14:45

Noora Kotaja, Turku Graduate School of Biomedical Sciences

Control of male germ cell differentiation by small regulatory RNAs

 

14:45-15:15

Fang Li, Institute of Biotechonology, Soochow University

The Characteristics of Placate Derived Stem Cells

 

15:15-15:30 Coffee break

 

Section 4: Chair Minna Taipale

 

 

15:30-16:00

Hanna Ollila, Helsinki Graduate School in Biotechnology and Molecular Biology Genetic background of sleep and depression

 

16:00-16:30

Songguang Ju, Institute of Biotechonology, Soochow University

4-1BBL reverse signaling and monocytic leukemia

 

16:30-17:00

Concluding session chaired by ZHANG Xueguang (SINO)

Concluding remarks by Dennis Bamford (FINN) ＆ Bairong Shen (SINO)

 

The Fourth Chinese Association of Life Science in Finland (CALSIF) Annual Meeting

University of Helsinki, Helsinki
October 31, 2009



Meeting Place:

Cajsa Room, 4th floor, Mannerheimintie 5 B, Helsinki

Contact information:

GSM 0440275578 Cheng Fang GSM 0405277708 Li Songping

Scientific Program

SATURDAY (31.10.2009)

9:30 -9:55         Registration and coffee

9:55 - 10:00     Opening remarks 


10:00-10:15     Zong Gang: Introduction of the Chinese policies to attract back oversea scholars

10:15-10:30     Tian Li: Neuronal regulation of immune responses in the central nervous system

10:30-10:45     Wu Jianmin: PINA: an integrated network analysis platform for protein-protein interactions

10:45-11:15      Interactive session with refreshments

11:15-11:30      Deng Xianbao: Tobacco Rattle Virus RNA1 as a vector to induce gene silencing on plants

11:30-11:45      Yu liying: Death pathways activated in the neurotrophic factor-deprived neurons

11:45-12:00      Cheng Fang: Functional genomics for understanding KSHV pathobiology

12:00-12:15      Zeng Zhao: Genome-wide RNAi screen identifies "CTV" as a novel

player in BMP signalling pathway 12:15-13:15 Presentations of other participants and discussion 13:15-13:30 Participants photography 13:30-14:30 Lunch 14:30-Closing of the meeting

Chinese Association of Life Science in Finland

November 25, 2006,Tampere,  Finland

9:30–10:00       Registration

10:00–10:05  Opening remarks (He Qiushui)

10:30-12:30 Session I (Chairman: Li Songping)

Academic presentations

10:30  Zhu Lei, Helsinki University: Detection of molecular forms of Prostate Specific Antigen

11:00  Fan Yuemei, Tampere  University: Hepatic lipase gene variation is related to coronary reactivity in healthy young men.

11:30   Wei Gonghong, Helsinki University: p38 signaling to chromatin modulates the induction of gamma-globin gene expression by apicidin in human erythroid cells

 

12:00 Chen Shangjun, Tampere University: Drosophila Sex-peptide and the stimulation of innate immune system

 

12:30-12:35 Participants photography

12:35-13:30 Lunch

13:30-16:30   Session II (Chairman: He Qiushui)

Research description of the CALSiF members and discussion of Cooperation with Suzhou and other universities (Select and organize delegation for the visiting and cooperation)

13:30-13:40 About cooperation with Suzhou (Shen Bairong)

13:50-16:30 Ten minutes of each presentation (every one should prepare a powerpoint presentation and it should include the significance of the research and perhaps the status of this research in China, what (projects) you would like to offer for the cooperate with China in future)

......

Fang Cheng: siRNA screening of KSHV

Ge Shichao: The Examination of Salmonella seriovr Enteritidis Genes during Infection of Human Monocytic U937 Cells using Microarray and Real Time RT-PCR

He Qiushui: Resurgence of a Vaccine Preventable Disease Pertussis in Immunized Populations

Hui Nan: open

Li Songping: Application of tandem affinity purification(TAP) method in the study of cell signaling

LIN FENG: open

Shen Bairong: Bioinformatics market

Yang Ying: Open

ZENG ZHAO: open

          .......

 

 

16:30-16:45    Coffee

16:45-17:30   Session III (Chairman : Shen Bairong)

Summary of CALSiF and its board election

17:30          Closing remarks

第二届留芬学人生命科学协会年会(2004年8月 14, 11:45------15日,11:45 )

地点:Suomen Raamattuopisto; Helsingintie 10; 02700 Kauniainen tel. 09- 5123910 (Bible Institute,赫尔辛基 神学院 )
The institute is very close to the railwaystation; from railway station, you can take trains S, U ,L and E. or bus 261

1) 8月14日

11.45 - 12.30 Lunch

12:30-12:40: Opening speech: Dr. HE QiuShui (Chairman of CALSiF)

12:40-14:10:Chairman: Dr. GUO Deying

12:40-13:25     SHEN Bairong,  Bioinformatics and Cancer

13:25-14:10     CHEN Tong,Infection, Immunity and Nobel Prize

14.10 - 14.25 Coffee

14.25 - 16.25 Chairman: Dr. SHEN Bairong 

14:25-15:10    CHENG Sulin

15:10-15:55     ZHANG Fuping,       knock-out and so on 

15:55-16:25     Sebastien DUPRAT, Globalisation of Science: Is the European model of diversity valid for research?

16.30 - 17.30    Dinner

17.30 - 18.30    Chairman: Dr. HE Yulong

17:30-18:00 LI XiaoDong

18:00-18:30 ZHANG XianZhi: HISTONE ACETYLATION STATUS REGULATES EOSINOPHIL

AND NEUTROPHIL APOPTOSIS

18:30-19:00 Jin Cong-Yu: histamine innervation and receptors in the human thalamocortical system and their alterations in the major mental disorders

 

19.00 - 23.00 Evening snack; 晚上娱乐活动,Sauna: 20:00-23:00



2)8月15日

7.30 - 10.00 Breakfast

10.00 - 10.15 Coffee

10:15-11:15 Chairman:  Dr. HE QiuShui

10:15-11:00介绍春辉计划

11:00-11:45中芬科技交流 (中国驻芬兰使馆教育处/科技处)

11:45-12:15 中华信息公司

12:15 Lunch and leaving

*Confirmed

本次活动赞助: 中华信息公司(www.chinainfo.fi) ;中国驻芬使馆教育处; 根据经费情况将给予适当交通费补助.

The Establishing Meeting and 1st Scientific Symposium of CALSiF,

January 24th, 2004

Vanha kelkkamäki 11, Helsinki, FinlandProgramme

 

Afternoon: 12:00-13:30

Opening section (Qiushui He)

Introduction of CALSiF

Guest speeches

Zhang zhijian (Ambassador)

Wu Shiguang

Liu Meng

Xie Gaofeng

Huang Zhigang

Section for the Constitution of CALSiF (Xiaojuan Meng)

Member’s self introduction (1 minute)

Discussion of the Constitution

Section voting (Bairong Shen)

Procedure for voting according to constitution

Voting and results showing

Chairman Speaking

Lunch

Afternoon: 1:30-17:00

Academic section (Chaired by the Board members)

Four scientific presentations

Afternoon: 17:00-18:00

Discussion for the plan in 2004 and concluding remarks

Abstracts of four scientific presentations

 

 

Presentation 1

 

Chen Suling: How to become a successful researcher?

Professor Chen will share her experiences on academic activity, such as, how to make your academic application and article more attractive and so on.

 

 

Presentation 2

 

Guo Deying:  SARS in China

Novel Subgenomic RNAs and Noncanonical Transcription Initiation Signal of Severe Acute Respiratory Syndrome Associated Coronavirus (SARS-CoV)

ABSTRACT: Severe acute respiratory syndrome (SARS) is a febrile respiratory illness. The disease has been etiologically linked to a novel coronavirus that has been named the SARS-associated coronavirus (SARS-CoV), with positive strand RNA genome of approximately 29.7Kb. Since it is a member of the Coronaviridae, a complex transcriptional, translational and posttranslational regulatory mechanisms is involved in SARS-CoV genome expression. The expressions of the genetic information of SARS-CoV involve synthesis of a set of successively smaller subgenomic mRNAs, which are responsible for synthesis of different viral structural and non-structural proteins. The exact number of SARS-CoV subgenomic mRNAs and molecular mechanism underlying the synthesis of SARS subgenomic RNA is still not clear. In order to address these questions, total RNA from SARS-CoV infected Vero cells was extracted and subjected to

Northern blot analysis with probes specific for 3¡ä non-translated region. Presence, exact number of subgenomic mRNAs, existence of their corresponding negative strand subgenomic RNAs and precise leader to body fusion sites were determined by RT-PCR and DNA sequencing.

We characterized 10 subgenomic mRNAs corresponding to ORFs S, S¡ä, X1, X2, E, M, X3, X4, X6 and N in SARS-CoV infected Vero cells. We are first to report the existence of two previously unrecognized novel subgenomic mRNAs termed as S¡ä and X2. Sequence analysis revealed leader body fusion site of the mRNA S¡ä is located 384 nucleotide downstream of the consensus Trans Regulatory Sequence (TRS) for the spike protein mRNA. Body TRS of the S¡ä have only four nucleotide homology with consensus TRS of SARS-CoV. ORF of S¡ä subgenomic mRNA is predicted to encode a 124.2 kd truncated spike protein. Leader to body fusion site of X2 subgenomic mRNA is located 13 nucleotide upstream of start codon ATG of predicted ORF 3B. ORF of X2 subgenomic mRNA is predicted to encode a 17.6 kd protein of unknown function. This is yet to be determined whether these sequences function independently as promoters and whether these mRNAs are functional massages. We also characterized the negative stra! nd subgenomic RNAs which are believed to act as template for synthesis of subgenomic mRNAs.

 

 

Presentation 3

 

Yang Hongyan: RNA-dependent RNA polymerases of cystoviruses

Among double-stranded (ds) RNA viruses, bacteriophage f6 P2 protein containing characteristic polymerase (Pol) motifs has been demonstrated to be the first recombinant active subunit, which is capable of catalyzing replication reaction without assistance of other proteins in vitro. The amino acid identities are only 20% to 50% for the Pol proteins among f6 and the new isolated f6 distant-related cystoviruses f8, f12, and f13.  In my thesis studies, the putative Pol (P2) enzymes of the new cystoviruses have been expressed, purified and characterized. Like f6 Pol, the purified P2 of f8, f12, and f13 were demonstrated to catalyze the RNA synthesis for replication and transcription, although with many distinct biochemical characteristics. And the mechanisms for transcription (dsRNA→ssRNA) polarity and replication initiation (ssRNA→dsRNA) were investigated. Two independent models of transcriptional polarity in Cystoviridae have been suggested: Pol affinity to (+) strand initiation sites and accessibility of these sites to the Pol in a single-stranded form. Similar to the Pol of dengue virus, the de novo initiation by cystovirus Pols is inhibited at elevated temperatures, whereas the elongation phase is relatively thermostable. Based on the specificity of f6 Pol capable of taking chain terminating nucleotide analogs, the cystoviral Pols were used in attempts to sequence the dsRNA genome of a novel adult rotavirus (NADRV) isolated from China in 1997. Our sequence data obtained with a single primer method strongly suggests that this NADRV does not belong to any known human rotavirus groups.

 

 

Presentation 4

 

He Yulong: Life is beautiful

It will be a general presentation about the current understanding of molecular mechanisms underlying the development of blood and lymphatic vascular systems.